GTX130482
PHD2 antibody
Cannot supply to this region.
- SKU:
- GTX130482
- Additional Names:
- egl-9 family hypoxia inducible factor 1 , C1orf12 , ECYT3 , HALAH , HIF-PH2 , HIFPH2 , HPH-2 , HPH2 , PHD2 , SM20 , ZMYND6
- Application:
- WB
- Concentration:
- 0.89 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human PHD2. The exact sequence is proprietary.
- Uniprot:
- Q9GZT9
- Synonyms:
- C1orf12;ECYT3;egl nine homolog 1;egl nine-like protein 1;HALAH;HIF-PH2;HIF-prolyl hydroxylase 2;HIFPH2;HPH-2;HPH2;hypoxia-inducible factor prolyl hydroxylase 2;PHD2;prolyl hydroxylase domain-containing protein 2;SM-20;SM20;zinc finger MYND domain-containing protein 6;ZMYND6
- Extra Details:
- The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq]
- Shipping Conditions:
- Blue Ice