GTX129604
Timeless antibody
Cannot supply to this region.
- SKU:
- GTX129604
- Additional Names:
- timeless circadian regulator , TIM , TIM1 , hTIM
- Application:
- WB, IF, ICC, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human TIMELESS. The exact sequence is proprietary.
- Uniprot:
- Q9UNS1
- Synonyms:
- hTIM;protein timeless homolog;TIM;TIM1;timeless circadian clock 1;timeless homolog;Tof1 homolog
- Extra Details:
- Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
- Shipping Conditions:
- Blue Ice