GTX128382
Mib antibody
Cannot supply to this region.
- SKU:
- GTX128382
- Additional Names:
- mindbomb E3 ubiquitin protein ligase 1 , cg5841 , chunp6889 , fe47f05 , im:7148100 , mib , wu:fe47f05
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Fish
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Fish
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of zebrafish Mib. The exact sequence is proprietary.
- Uniprot:
- Q804S5
- Synonyms:
- cg5841;chunp68;chunp6889;E3 ubiquitin-protein ligase mib1;fe47f05;im:714810;im:7148100;mi;mib;mind bomb;mindbomb E3 ubiquitin protein ligase 1;protein mind bomb;RING-type E3 ubiquitin transferase mib1;white tail;wi;wit;wu:fe47f05
- Extra Details:
- E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intestine. Essential for early embryonic development.
- Shipping Conditions:
- Blue Ice