MYSM1 antibody

Cannot supply to this region.

SKU:: GTX128254
Additional Names:: Myb like, SWIRM and MPN domains 1 , 2A-DUB , 2ADUB , BMFS4
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human MYSM1. The exact sequence is proprietary.
Uniprot:: Q5VVJ2
Synonyms:: 2A-DUB;2ADUB;BMFS4;deubiquitinase MYSM1;histone H2A deubiquitinase MYSM1;myb-like, SWIRM and MPN domain-containing protein 1
Extra Details:: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.