TPO antibody [MoAb47]

Cannot supply to this region.

SKU:: GTX12500
Additional Names:: thyroid peroxidase , MSA , TDH2A , TPX
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Human thyroid peroxidase (hTPO) purified from thyroid microsomes by immunoaffinity chromatography.
Clone:: MoAb47
Uniprot:: P07202
Synonyms:: MSA;TDH2A;thyroid microsomal antigen;thyroid peroxidase;thyroperoxidase;TPX
Extra Details:: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]