GTX12498
AMACR antibody
Cannot supply to this region.
- SKU:
- GTX12498
- Additional Names:
- alpha-methylacyl-CoA racemase , AMACRD , CBAS4 , P504S , RACE , RM
- Application:
- IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Purified
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- A synthetic human AMACR peptide.
- Uniprot:
- Q9UHK6
- Synonyms:
- 2-methylacyl-CoA racemase;alpha-methylacyl-CoA racemase;AMACRD;CBAS4;P504S;RACE;RM
- Extra Details:
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
- Shipping Conditions:
- Blue Ice