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  2. Polyclonal

GTX122197

KLB antibody [N1N3]

Cannot supply to this region.

SKU:
GTX122197
Additional Names:
klotho beta , BKL
Application:
WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human, Mouse
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Mouse
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the Extracellular domain of human KLB. The exact sequence is proprietary.
Clone:
N1N3
Uniprot:
Q86Z14
Synonyms:
b-Klotho;beta-klotho;betaKlotho;BKL;klotho beta like;klotho beta-like protein
Extra Details:
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
Shipping Conditions:
Blue Ice