GTX121563
RASA4 antibody
Cannot supply to this region.
- SKU:
- GTX121563
- Additional Names:
- RAS p21 protein activator 4 , CAPRI , GAPL
- Application:
- WB, IF, ICC
- Concentration:
- 0.9 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human RASA4. The exact sequence is proprietary.
- Uniprot:
- O43374
- Synonyms:
- Ca2+-promoted Ras inactivator;calcium-promoted Ras inactivator;CAPRI;GAPL;ras GTPase-activating protein 4;Ras p21 protein activator 4;rasGAP-activating-like protein 2
- Extra Details:
- This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice