UBXN1 antibody

Cannot supply to this region.

SKU:: GTX121127
Additional Names:: UBX domain protein 1 , 2B28 , SAKS1 , UBXD10
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.78 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human UBXN1. The exact sequence is proprietary.
Uniprot:: Q04323
Synonyms:: 2B28;SAKS1;SAPK substrate protein 1;UBA/UBX 33.3 kDa protein;UBX domain-containing protein 1;UBXD10
Extra Details:: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.