GTX12084
HSD17B4 antibody
Cannot supply to this region.
- SKU:
- GTX12084
- Application:
- WB, IHC-P
- Concentration:
- 500 ug/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA, 0.025% Thimerosal, 0.025% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human Hydroxysteroid(17-beta) Dehydrogenase 4(744-761aa NIMLSQKLQMILKDYAKL), identical to the related rat and mouse sequences.
- Uniprot:
- P51659
- Synonyms:
- 17-beta-HSD 4;17-beta-HSD IV;17-beta-hydroxysteroid dehydrogenase 4;17beta-estradiol dehydrogenase type IV;3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase;beta-hydroxyacyl dehydrogenase;beta-keto-reductase;D-3-hydroxyacyl-CoA dehydratase;D-bifunctional protein;D-bifunctional protein, peroxisomal;DBP;epididymis secretory sperm binding protein;hydroxysteroid dehydrogenase 4;MFE-2;MFP-2;MPF-2;multifunctional protein 2;peroxisomal multifunctional enzyme type 2;peroxisomal multifunctional protein 2;PRLTS1;SDR8C1;short chain dehydrogenase/reductase family 8C member 1
- Extra Details:
- The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- Shipping Conditions:
- Blue Ice