GTX120114
DYNC1LI1 antibody
Cannot supply to this region.
- SKU:
- GTX120114
- Additional Names:
- dynein cytoplasmic 1 light intermediate chain 1 , DLC-A , DNCLI1 , LIC1
- Application:
- WB, IHC-P, IF, ICC, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human DYNC1LI1. The exact sequence is proprietary.
- Uniprot:
- Q9Y6G9
- Synonyms:
- cytoplasmic dynein 1 light intermediate chain 1;DLC-A;DNCLI1;dynein light chain A;dynein light intermediate chain 1, cytosolic;dynein, cytoplasmic, light intermediate polypeptide 1;LIC1
- Extra Details:
- Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
- Shipping Conditions:
- Blue Ice