GTX119877
THOC7 antibody
Cannot supply to this region.
- SKU:
- GTX119877
- Additional Names:
- THO complex 7 , NIF3L1BP1 , fSAP24 , hTREX30
- Application:
- WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human THOC7. The exact sequence is proprietary.
- Uniprot:
- Q6I9Y2
- Synonyms:
- fSAP24;functional spliceosome-associated protein 24;hTREX30;Ngg1 interacting factor 3 like 1 binding protein 1;ngg1-interacting factor 3-like protein 1-binding protein 1;NIF3L1-binding protein 1;NIF3L1BP1;THO complex 7 homolog;THO complex subunit 7 homolog
- Extra Details:
- Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.
- Shipping Conditions:
- Blue Ice