Macro H2A.2 antibody [N1C1]

Cannot supply to this region.

SKU:: GTX119657
Additional Names:: H2A histone family member Y2 , macroH2A2
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human Macro H2A.2. The exact sequence is proprietary.
Clone:: N1C1
Uniprot:: Q9P0M6
Synonyms:: core histone macro-H2A.2;core histone macroH2A2.2;H2A histone family member Y2;H2AFY2;histone macroH2A2;mH2A2
Extra Details:: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.