![NTAN1 antibody [N1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX119378/GTX119378_40344_IHC_w_23060519_768.webp)
![NTAN1 antibody [N1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX119378/GTX119378_WB_w_23060519_591.webp)
GTX119378
NTAN1 antibody [N1C3]
Cannot supply to this region.
- SKU:
- GTX119378
- Additional Names:
- N-terminal asparagine amidase , PNAA , PNAD
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human NTAN1. The exact sequence is proprietary.
- Clone:
- N1C3
- Uniprot:
- Q96AB6
- Synonyms:
- PNAA;PNAD;protein N-terminal Asn amidase;protein N-terminal asparagine amidase;protein N-terminal asparagine amidohydrolase;Protein NH2-terminal asparagine amidohydrolase;protein NH2-terminal asparagine deamidase;protein NTN-amidase
- Extra Details:
- Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position.
- Shipping Conditions:
- Blue Ice