GTX119361
ITM2B antibody
Cannot supply to this region.
- SKU:
- GTX119361
- Additional Names:
- integral membrane protein 2B , ABRI , BRI , BRI2 , BRICD2B , E25B , E3-16 , FBD , RDGCA , imBRI2
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 0.67 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ITM2B. The exact sequence is proprietary.
- Uniprot:
- Q9Y287
- Synonyms:
- ABRI;ABri/ADan amyloid peptide;BRI;BRI2;BRICD2B;BRICHOS domain containing 2B;E25B;E3-16;epididymis secretory sperm binding protein;FBD;imBRI2;immature BRI2;integral membrane protein 2B;Protein E25B;RDGCA;transmembrane protein BRI
- Extra Details:
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice