Rffl antibody [N2C3]

Cannot supply to this region.

SKU:: GTX117832
Additional Names:: ring finger and FYVE like domain containing E3 ubiquitin protein ligase , CARP-2 , CARP2 , FRING , RIFIFYLIN , RNF189 , RNF34L
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human Rffl. The exact sequence is proprietary.
Clone:: N2C3
Uniprot:: Q8WZ73
Synonyms:: CARP-2;CARP2;caspase 8 and 10 associated RING protein-2;caspase regulator CARP2;caspases-8 and -10-associated RING finger protein 2;E3 ubiquitin-protein ligase rififylin;FRING;FYVE-RING finger protein SAKURA;RIFIFYLIN;ring finger and FYVE-like domain containing 1;RING finger and FYVE-like domain-containing protein 1;RING finger protein 189;RING finger protein 34-like;RING-type E3 ubiquitin transferase rififylin;RNF189;RNF34L
Extra Details:: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.