![GRAF antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX117598/GTX117598_40555_WB_w_23060519_598.webp)
GTX117598
GRAF antibody [C2C3], C-term
Cannot supply to this region.
- SKU:
- GTX117598
- Additional Names:
- Rho GTPase activating protein 26 , GRAF , GRAF1 , OPHN1L , OPHN1L1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human GRAF. The exact sequence is proprietary.
- Clone:
- C2C3
- Uniprot:
- Q9UNA1
- Synonyms:
- GRAF;GRAF1;GTPase regulator associated with focal adhesion kinase;GTPase regulator associated with focal adhesion kinase pp125(FAK);oligophrenin-1-like protein;OPHN1L;OPHN1L1;rho GTPase-activating protein 26;Rho-type GTPase-activating protein 26
- Extra Details:
- Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice