GTX117559
PCMT1 antibody
Cannot supply to this region.
- SKU:
- GTX117559
- Additional Names:
- protein-L-isoaspartate (D-aspartate) O-methyltransferase , PIMT
- Application:
- WB
- Concentration:
- 0.75 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human PCMT1. The exact sequence is proprietary.
- Uniprot:
- P22061
- Synonyms:
- epididymis secretory sperm binding protein;L-isoaspartyl protein carboxyl methyltransferase;PIMT;protein L-isoaspartyl/D-aspartyl methyltransferase;protein-beta-aspartate methyltransferase;protein-L-isoaspartate(D-aspartate) O-methyltransferase
- Extra Details:
- This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
- Shipping Conditions:
- Blue Ice