GTX117141
ZP2 antibody
Cannot supply to this region.
- SKU:
- GTX117141
- Additional Names:
- zona pellucida glycoprotein 2 , ZPA , Zp-2
- Application:
- WB, IHC-P
- Concentration:
- 0.89 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Recombinant protein encompassing a sequence within the Extracellular domain of human ZP2. The exact sequence is proprietary.
- Uniprot:
- Q05996
- Synonyms:
- OOMD6;Zona pellucida glycoprotein 2;zona pellucida glycoprotein 2 (sperm receptor);zona pellucida glycoprotein ZP2;zona pellucida protein A;zona pellucida sperm-binding protein 2;Zp-2;ZPA
- Extra Details:
- The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice