SIN3B antibody [N1N2], N-term

Cannot supply to this region.

SKU:: GTX116326
Additional Names:: SIN3 transcription regulator family member B
Application:: WB, IHC-P, IF, ICC, IP
Concentration:: 0.96 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human SIN3B. The exact sequence is proprietary.
Clone:: N1N2
Uniprot:: O75182
Synonyms:: histone deacetylase complex subunit Sin3b;paired amphipathic helix protein Sin3b;SIN3 homolog B, transcriptional regulator;SIN3 transcription regulator homolog B;transcriptional corepressor Sin3b
Extra Details:: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.