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![MBD3 antibody [N1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX116204/GTX116204_WB_w_23060519_844.webp)
GTX116204
MBD3 antibody [N1C3]
Cannot supply to this region.
- SKU:
- GTX116204
- Additional Names:
- methyl-CpG binding domain protein 3
- Application:
- WB
- Concentration:
- 0.51 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human MBD3. The exact sequence is proprietary.
- Clone:
- N1C3
- Uniprot:
- O95983
- Synonyms:
- methyl-CpG-binding domain protein 3;Methyl-CpG-binding protein MBD3
- Extra Details:
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice