GTX116008
MAP4K4 antibody
Cannot supply to this region.
- SKU:
- GTX116008
- Additional Names:
- mitogen-activated protein kinase kinase kinase kinase 4 , FLH21957 , HEL-S-31 , HGK , MEKKK4 , NIK
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 0.19 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MAP4K4. The exact sequence is proprietary.
- Uniprot:
- O95819
- Synonyms:
- epididymis secretory protein Li 31;FLH21957;HEL-S-31;hepatocyte progenitor kinase-like/germinal center kinase-like kinase;HGK;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK4;mitogen-activated protein kinase kinase kinase kinase 4;nck-interacting kinase;NIK;Ste20 group protein kinase HGK
- Extra Details:
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice