MTBP antibody [N1N3]

Cannot supply to this region.

SKU:: GTX115837
Additional Names:: MDM2 binding protein , MDM2BP
Application:: WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human MTBP. The exact sequence is proprietary.
Clone:: N1N3
Uniprot:: Q96DY7
Synonyms:: MDM2 (mouse double minute 2)-binding protein, 104kD;mdm2-binding protein;Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa;MDM2BP
Extra Details:: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.