GTX115667
SWAP70 antibody
Cannot supply to this region.
- SKU:
- GTX115667
- Additional Names:
- switching B cell complex subunit SWAP70 , HSPC321 , SWAP-70
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human SWAP70. The exact sequence is proprietary.
- Uniprot:
- Q9UH65
- Synonyms:
- HSPC321;SWAP switching B-cell complex 70kDa subunit;SWAP switching B-cell complex subunit 70;SWAP-70;switch-associated protein 70
- Extra Details:
- Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
- Shipping Conditions:
- Blue Ice