Endostatin antibody

Cannot supply to this region.

SKU:: GTX11525
Additional Names:: collagen, type XVIII, alpha 1
Application:: ELISA, WB, IHC-Fr
Physical State:: Liquid
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Goat
Reactivities:: Mouse
Buffer:: PBS, 5% Trehalose, no preservatives.
Immunogen:: purified recombinant mouse endostatin expressed in Sf21 cells.
Uniprot:: P39061
Synonyms:: alpha-1(XVIII) collagen;collagen alpha-1(XVIII) chain;endo;endostatin;procollagen, type XVIII, alpha 1
Extra Details:: Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.