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  2. Polyclonal

GTX115123

HYAL2 antibody [N2C2], Internal

Cannot supply to this region.

SKU:
GTX115123
Additional Names:
hyaluronidase 2 , LUCA2
Application:
WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human HYAL2. The exact sequence is proprietary.
Clone:
N2C2
Uniprot:
Q12891
Synonyms:
hyal-2;hyaluronidase-2;hyaluronoglucosaminidase 2;Hyaluronoglucosaminidase-2;LUCA2;lung carcinoma protein 2;lysosomal hyaluronidase;PH-20 homolog;PH20 homolog
Extra Details:
This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein. It has been described as a lysosomal hyaluronidase which is active at a pH below 4 and specifically hydrolyzes high molecular weight hyaluronan. It has also been described as a GPI-anchored cell surface protein which does not display hyaluronidase activity but does serve as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR. [provided by RefSeq]
Shipping Conditions:
Blue Ice