STAM antibody [N2C2], Internal

Cannot supply to this region.

SKU:: GTX115060
Additional Names:: signal transducing adaptor molecule , STAM-1 , STAM1
Application:: WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human STAM. The exact sequence is proprietary.
Clone:: N2C2
Uniprot:: Q92783
Synonyms:: HSE1 homolog;signal transducing adapter molecule 1;signal transducing adaptor molecule (SH3 domain and ITAM motif) 1;STAM-1;STAM1
Extra Details:: This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein. [provided by RefSeq]

Shipping Conditions:: Blue Ice