GTX114690
ABCD4 antibody
Cannot supply to this region.
- SKU:
- GTX114690
- Additional Names:
- ATP binding cassette subfamily D member 4 , ABC41 , EST352188 , MAHCJ , P70R , P79R , PMP69 , PXMP1L
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 0.89 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human ABCD4. The exact sequence is proprietary.
- Uniprot:
- O14678
- Synonyms:
- 69 kDa peroxisomal ABC-transporter;ABC41;ATP-binding cassette sub-family D member 4;ATP-binding cassette, sub-family D (ALD), member 4;EST352188;lysosomal cobalamin transporter ABCD4;MAHCJ;P70R;P79R;Peroxisomal membrane protein 1-like;peroxisomal membrane protein 69;PMP69;PMP70-related protein;PXMP1-L;PXMP1L
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice