PPP3CC antibody [N1C1]

Cannot supply to this region.

SKU:: GTX114660
Additional Names:: protein phosphatase 3 catalytic subunit gamma , CALNA3 , CNA3 , PP2Bgamma
Application:: WB
Concentration:: 0.55 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human PPP3CC. The exact sequence is proprietary.
Clone:: N1C1
Uniprot:: P48454
Synonyms:: calcineurin, testis-specific catalytic subunit;Calmodulin-dependent calcineurin A subunit gamma isoform;CALNA3;CAM-PRP catalytic subunit;CNA3;PP2Bgamma;protein phosphatase 3, catalytic subunit, gamma isozyme;serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Extra Details:: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]

Shipping Conditions:: Blue Ice