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![PDZK1 antibody [C1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX114628/GTX114628_WB_w_23060518_758.webp)
GTX114628
PDZK1 antibody [C1C3]
Cannot supply to this region.
- SKU:
- GTX114628
- Additional Names:
- PDZ domain containing 1 , CAP70 , CLAMP , NHERF-3 , NHERF3 , PDZD1
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human PDZK1. The exact sequence is proprietary.
- Clone:
- C1C3
- Uniprot:
- Q5T2W1
- Synonyms:
- CAP70;CFTR-associated protein of 70 kDa;CLAMP;Na(+)/H(+) exchange regulatory cofactor NHE-RF3;Na(+)/H(+) exchanger regulatory factor 3;na/Pi cotransporter C-terminal-associated protein 1;naPi-Cap1;NHERF-3;NHERF3;PDZ domain-containing protein 1;PDZ-containing kidney protein 1;PDZD1;sodium-hydrogen exchanger regulatory factor 3
- Extra Details:
- A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
- Shipping Conditions:
- Blue Ice