HMGCL antibody [N2C3]

Cannot supply to this region.

SKU:: GTX114472
Additional Names:: 3-hydroxy-3-methylglutaryl-CoA lyase , HL
Application:: WB, IHC-P
Concentration:: 0.44 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human HMGCL. The exact sequence is proprietary.
Clone:: N2C3
Uniprot:: P35914
Synonyms:: 3-hydroxy-3-methylglutarate-CoA lyase;3-hydroxymethyl-3-methylglutaryl-CoA lyase;3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase;HL;HMG-CoA lyase;hydroxymethylglutaricaciduria;hydroxymethylglutaryl-CoA lyase, mitochondrial;mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Extra Details:: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]