GTX114404
FGD1 antibody
Cannot supply to this region.
- SKU:
- GTX114404
- Additional Names:
- FYVE, RhoGEF and PH domain containing 1 , AAS , FGDY , MRXS16 , ZFYVE3
- Application:
- WB
- Concentration:
- 0.85 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human FGD1. The exact sequence is proprietary.
- Uniprot:
- P98174
- Synonyms:
- AAS;faciogenital dysplasia 1 protein;FGDY;FYVE, RhoGEF and PH domain-containing protein 1;MRXS16;rho/Rac GEF;rho/Rac guanine nucleotide exchange factor FGD1;ZFYVE3;zinc finger FYVE domain-containing protein 3
- Extra Details:
- FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice