GTX114123
TREX1 antibody
Cannot supply to this region.
- SKU:
- GTX114123
- Additional Names:
- three prime repair exonuclease 1 , AGS1 , CRV , DRN3 , HERNS
- Application:
- WB
- Concentration:
- 0.75 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human TREX1. The exact sequence is proprietary.
- Uniprot:
- Q9NSU2
- Synonyms:
- 3' repair exonuclease 1;3'-5' exonuclease TREX1;AGS1;CRV;deoxyribonuclease III;DNase III;DRN3;HERNS;RVCLS;three-prime repair exonuclease 1
- Extra Details:
- This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice