![RAD18 antibody [N1C1]](https://www.genetex.com/upload/website/prouct_img/normal/GTX113987/GTX113987_40150_IFA_w_23060501_328.webp)
![RAD18 antibody [N1C1]](https://www.genetex.com/upload/website/prouct_img/normal/GTX113987/GTX113987_IHC_w_23060501_414.webp)
GTX113987
RAD18 antibody [N1C1]
Cannot supply to this region.
- SKU:
- GTX113987
- Additional Names:
- RAD18 E3 ubiquitin protein ligase , RNF73
- Application:
- IHC-P, IF, ICC
- Concentration:
- 0.46 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol; 1% BSA, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human RAD18. The exact sequence is proprietary.
- Clone:
- N1C1
- Uniprot:
- Q9NS91
- Synonyms:
- E3 ubiquitin-protein ligase RAD18;hHR18;hRAD18;postreplication repair protein hRAD18p;postreplication repair protein RAD18;RAD18 homolog;RAD18, S. cerevisiae, homolog;RING finger protein 73;RING-type E3 ubiquitin transferase RAD18;RNF73
- Extra Details:
- The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice