BACE2 antibody [C1C3]

Cannot supply to this region.

SKU:: GTX113951
Additional Names:: beta-secretase 2 , AEPLC , ALP56 , ASP1 , ASP21 , BAE2 , CDA13 , CEAP1 , DRAP
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.83 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human BACE2. The exact sequence is proprietary.
Clone:: C1C3
Uniprot:: Q9Y5Z0
Synonyms:: 56 kDa aspartic-like protease;AEPLC;ALP56;ASP1;ASP21;Aspartic-like protease 56 kDa;aspartyl protease 1;BAE2;beta-secretase 2;beta-site amyloid beta A4 precursor protein-cleaving enzyme 2;Beta-site amyloid precursor protein cleaving enzyme 2;beta-site APP-cleaving enzyme 2;CDA13;CEAP1;Down region aspartic protease;Down syndrome region aspartic protease;DRAP;memapsin-1;membrane-associated aspartic protease 1;SLCO3A1/BACE2 fusion;theta-secretase;transmembrane aspartic proteinase Asp1
Extra Details:: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Shipping Conditions:: Blue Ice