DPYD antibody [N1N2], N-term

Cannot supply to this region.

SKU:: GTX113672
Additional Names:: dihydropyrimidine dehydrogenase , DHP , DHPDHASE , DPD
Application:: WB, IHC-P
Concentration:: 0.59 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary.
Clone:: N1N2
Uniprot:: Q12882
Synonyms:: DHP;DHPDHASE;dihydropyrimidine dehydrogenase [NADP(+)];dihydrothymine dehydrogenase;dihydrouracil dehydrogenase;DPD
Extra Details:: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. [provided by RefSeq]