RCC1 antibody [N1C1]

Cannot supply to this region.

SKU:: GTX113402
Additional Names:: regulator of chromosome condensation 1 , CHC1 , RCC1-I , SNHG3-RCC1
Application:: WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human RCC1. The exact sequence is proprietary.
Clone:: N1C1
Uniprot:: P18754
Synonyms:: cell cycle regulatory protein;CHC1;Chromosome condensation protein 1;guanine nucleotide-releasing protein;RCC1-I;regulator of chromosome condensation;SNHG3-RCC1;SNHG3-RCC1 readthrough
Extra Details:: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.