![Thymidylate synthase antibody [N3C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX113289/GTX113289_42480_20160519_WB_w_23060501_272.webp)
![Thymidylate synthase antibody [N3C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX113289/GTX113289_42480_20160519_WB_Z_eye_22111423_672.webp)
GTX113289
Thymidylate synthase antibody [N3C3]
Cannot supply to this region.
- SKU:
- GTX113289
- Additional Names:
- thymidylate synthetase , HST422 , TMS , TS
- Application:
- WB
- Concentration:
- 0.53 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Fish, Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Thymidylate synthase. The exact sequence is proprietary.
- Clone:
- N3C3
- Uniprot:
- P04818
- Synonyms:
- HST422;thymidylate synthase;TMS;TS;TSase
- Extra Details:
- Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice