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  2. Polyclonal

GTX112673

MUL1 antibody

Cannot supply to this region.

SKU:
GTX112673
Additional Names:
mitochondrial E3 ubiquitin protein ligase 1 , C1orf166 , GIDE , MAPL , MULAN , RNF218
Application:
WB, IHC-P, IF, ICC
Concentration:
0.97 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Insect/Arthropod
Buffer:
PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human MUL1. The exact sequence is proprietary.
Uniprot:
Q969V5
Synonyms:
C1orf166;E3 SUMO-protein ligase MUL1;E3 ubiquitin ligase;E3 ubiquitin-protein ligase MUL1;GIDE;growth inhibition and death E3 ligase;MAPL;mitochondria-anchored protein ligase;mitochondrial E3 ubiquitin ligase 1;mitochondrial ubiquitin ligase activator of NF-kB;mitochondrial ubiquitin ligase activator of NFKB 1;mitochondrial-anchored protein ligase;MULAN;protein Hades;putative NF-kappa-B-activating protein 266;ring finger protein 218;RING-type E3 ubiquitin transferase NFKB 1;RNF218
Extra Details:
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Shipping Conditions:
Blue Ice