RBPJK antibody [C1C3]

Cannot supply to this region.

SKU:: GTX112358
Additional Names:: recombination signal binding protein for immunoglobulin kappa J region , AOS3 , CBF1 , IGKJRB , IGKJRB1 , KBF2 , RBP-J , RBPJK , RBPSUH , SUH , csl
Application:: WB, IF, ICC
Concentration:: 0.75 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human RBPJK. The exact sequence is proprietary.
Clone:: C1C3
Uniprot:: Q06330
Synonyms:: AOS3;CBF-1;CBF1;csl;H-2K binding factor-2;IGKJRB;IGKJRB1;immunoglobulin kappa J region recombination signal binding protein 1;J kappa-recombination signal-binding protein;KBF2;RBP-J;RBP-J kappa;RBP-JK;RBPJK;RBPSUH;recombining binding protein suppressor of hairless;renal carcinoma antigen NY-REN-30;SUH;suppressor of hairless homolog
Extra Details:: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

Shipping Conditions:: Blue Ice