PDE3A antibody [N3C1], Internal

Cannot supply to this region.

SKU:: GTX112305
Additional Names:: phosphodiesterase 3A , CGI-PDE , CGI-PDE A , CGI-PDE-A , HTNB
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human PDE3A. The exact sequence is proprietary.
Clone:: N3C1
Uniprot:: Q14432
Synonyms:: cAMP phosphodiesterase, myocardial cGMP-inhibited;CGI-PDE;CGI-PDE A;CGI-PDE-A;cGMP-inhibited 3',5'-cyclic phosphodiesterase A;cyclic GMP-inhibited phosphodiesterase A;HTNB;phosphodiesterase 3A, cGMP-inhibited
Extra Details:: Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).[supplied by OMIM]