CYP21A2 antibody [N2C3]

Cannot supply to this region.

SKU:: GTX112135
Additional Names:: cytochrome P450 family 21 subfamily A member 2 , CA21H , CAH1 , CPS1 , CYP21 , CYP21B , P450c21B
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human CYP21A2. The exact sequence is proprietary.
Clone:: N2C3
Uniprot:: P08686
Synonyms:: 21-OHase;CA21H;CAH1;CPS1;CYP21;CYP21B;Cytochrome P-450c21;Cytochrome P450 21;cytochrome P450 XXI;Cytochrome P450-C21;cytochrome P450-C21B;cytochrome P450, family 21, subfamily A, polypeptide 2;cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2;P450c21B;steroid 21 hydroxylase;steroid 21-hydroxylase;steroid 21-monooxygenase
Extra Details:: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Shipping Conditions:: Blue Ice