NKIRAS2 antibody [C2C3], C-term

Cannot supply to this region.

SKU:: GTX112075
Additional Names:: NFKB inhibitor interacting Ras like 2 , KBRAS2 , kappaB-Ras2
Application:: WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NKIRAS2. The exact sequence is proprietary.
Clone:: C2C3
Uniprot:: Q9NYR9
Synonyms:: I-kappa-B-interacting Ras-like protein 2;kappa B-Ras protein 2;kappaB-Ras2;KBRAS2;NF-kappa-B inhibitor-interacting Ras-like protein 2;NFKB inhibitor interacting Ras-like protein 2
Extra Details:: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.