MSH6 antibody [C1C2], Internal

Cannot supply to this region.

SKU:: GTX111661
Additional Names:: mutS homolog 6 , GTBP , GTMBP , HNPCC5 , HSAP , p160
Application:: IHC, WB, IHC-P, IF, ICC, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Fish, Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human MSH6. The exact sequence is proprietary.
Clone:: C1C2
Uniprot:: P52701
Synonyms:: DNA mismatch repair protein Msh6;G/T mismatch-binding protein;GTBP;GTMBP;HNPCC5;HSAP;MMRCS3;mutS protein homolog 6;mutS-alpha 160 kDa subunit;p160;sperm-associated protein
Extra Details:: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq]

Shipping Conditions:: Blue Ice