GTX111618
ASZ1 antibody
Cannot supply to this region.
- SKU:
- GTX111618
- Additional Names:
- ankyrin repeat, SAM and basic leucine zipper domain containing 1 , ALP1 , ANKL1 , C7orf7 , CT1.19 , GASZ , Orf3
- Application:
- WB, IHC-P
- Concentration:
- 0.77 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ASZ1. The exact sequence is proprietary.
- Uniprot:
- Q8WWH4
- Synonyms:
- ALP1;ANKL1;ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1;ankyrin-like 1;ankyrin-like protein 1;C7orf7;CT1.19;GASZ;germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein;Orf3
- Extra Details:
- Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
- Shipping Conditions:
- Blue Ice