MATK antibody [N3C3]

Cannot supply to this region.

SKU:: GTX111326
Additional Names:: megakaryocyte-associated tyrosine kinase , CHK , CTK , HHYLTK , HYL , HYLTK , Lsk
Application:: WB
Concentration:: 0.83 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human MATK. The exact sequence is proprietary.
Clone:: N3C3
Uniprot:: P42679
Synonyms:: CHK;CSK homologous kinase;Csk-homologous kinase;Csk-type protein tyrosine kinase;CTK;hematopoietic consensus tyrosine-lacking kinase;HHYLTK;hydroxyaryl-protein kinase;HYL;HYL tyrosine kinase;HYLTK;leukocyte carboxyl-terminal src kinase related;Lsk;megakaryocyte-associated tyrosine-protein kinase;protein kinase HYL;tyrosine kinase MATK;tyrosine-protein kinase CTK;tyrosylprotein kinase
Extra Details:: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq]

Shipping Conditions:: Blue Ice