![DDR1 antibody [C1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX111312/GTX111312_40464_IHC_w_23060500_944.webp)
![DDR1 antibody [C1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX111312/GTX111312_40464_WB_w_23060500_849.webp)
GTX111312
DDR1 antibody [C1C3]
Cannot supply to this region.
- SKU:
- GTX111312
- Additional Names:
- discoidin domain receptor tyrosine kinase 1 , CAK , CD167 , DDR , EDDR1 , HGK2 , MCK10 , NEP , NTRK4 , PTK3 , PTK3A , RTK6 , TRKE
- Application:
- WB, IHC-P
- Concentration:
- 1.03 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the Intracellular domain of human DDR1. The exact sequence is proprietary.
- Clone:
- C1C3
- Uniprot:
- Q08345
- Synonyms:
- CAK;CD167;CD167 antigen-like family member A;cell adhesion kinase;DDR;Discoidin receptor tyrosine kinase;EDDR1;epithelial discoidin domain-containing receptor 1;HGK2;mammary carcinoma kinase 10;MCK10;NEP;neuroepithelial tyrosine kinase;neurotrophic tyrosine kinase, receptor, type 4;NTRK4;Protein-tyrosine kinase 3A;protein-tyrosine kinase RTK-6;PTK3;PTK3A;PTK3A protein tyrosine kinase 3A;RTK6;TRK E;TRKE;tyrosine kinase DDR;tyrosine-protein kinase CAK
- Extra Details:
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice