CARD10 antibody [N2C1], Internal

Cannot supply to this region.

SKU:: GTX111222
Additional Names:: caspase recruitment domain family member 10 , BIMP1 , CARMA3
Application:: WB, IHC-P, IHC-Fr
Concentration:: 1.25 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human CARD10. The exact sequence is proprietary.
Clone:: N2C1
Uniprot:: Q9BWT7
Synonyms:: Bcl10 binding protein and activator of NFKB;BIMP1;CARD-containing MAGUK 3 protein;CARD-containing MAGUK protein 3;carma 3;CARMA3;caspase recruitment domain-containing protein 10
Extra Details:: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM]