Hec1 antibody

Cannot supply to this region.

SKU:: GTX110735
Additional Names:: NDC80 kinetochore complex component , HEC , HEC1 , HsHec1 , KNTC2 , TID3 , hsNDC80
Application:: WB, IP
Concentration:: 0.46 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein corresponding to human HEC1.
Uniprot:: O14777
Synonyms:: HEC;HEC1;highly expressed in cancer protein;highly expressed in cancer, rich in leucine heptad repeats;HsHec1;hsNDC80;kinetochore associated 2;kinetochore protein Hec1;kinetochore protein NDC80 homolog;kinetochore-associated protein 2;KNTC2;NDC80 homolog, kinetochore complex component;NDC80 kinetochore complex component homolog;retinoblastoma-associated protein HEC;TID3
Extra Details:: HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM]