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  2. Polyclonal

GTX110556

PCMT1 antibody

Cannot supply to this region.

SKU:
GTX110556
Additional Names:
protein-L-isoaspartate (D-aspartate) O-methyltransferase , PIMT
Application:
WB, IHC-P, IF, ICC
Concentration:
0.96 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human PCMT1. The exact sequence is proprietary.
Uniprot:
P22061
Synonyms:
epididymis secretory sperm binding protein;L-isoaspartyl protein carboxyl methyltransferase;PIMT;protein L-isoaspartyl/D-aspartyl methyltransferase;protein-beta-aspartate methyltransferase;protein-L-isoaspartate(D-aspartate) O-methyltransferase
Extra Details:
This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Shipping Conditions:
Blue Ice